A Case of Carcinosarcoma in a Patient with Corrosive Esophagitis.
- Author:
Ju Hyun OAK
1
;
Woo Chul CHUNG
;
Ji Han JUNG
;
Jin Dong KIM
;
Jeong Rok LEE
;
Chang Nyol PAIK
;
Kang Moon LEE
;
Kyu Do CHO
Author Information
1. Departments of Internal Medicine, College of Medicine, The Catholic University of Korea, St. Vincent's Hospital, Suwon, Korea. jwchulkr@yahoo.co.kr
- Publication Type:Case Report ; English Abstract
- Keywords:
Carcinosarcoma;
Esophagus;
Corrosive esophagitis
- MeSH:
Aged;
Carcinosarcoma/*diagnosis/pathology/surgery;
Esophageal Neoplasms/*diagnosis/pathology/surgery;
Esophagectomy;
Esophagitis/chemically induced;
Humans;
Male;
Tomography, X-Ray Computed;
Tumor Markers, Biological/immunology
- From:The Korean Journal of Gastroenterology
2008;52(1):42-47
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Carcinosarcoma of the esophagus is a rare malignancy accounting for approximately 1-2% of all esophageal neoplasms. It presents as a bulky intraluminal polypoid lesion mainly in the mid to lower esophagus, which harbors both carcinomatous and sarcomatous components histologically. It often presents relatively early because of its rapid intraluminal growth. We report the case of a 69-year-old man who had suffered from dysphagia for 1 month. He was previously admitted to the hospital due to corrosive esophagitis caused by ingestion of acetic acid. Endoscopy and radiological studies revealed a bulky polypoid mass with superficial ulcerations and mucosal friability, measuring 10 cm in length approximately, in the mid-esophagus. Subtotal esophagectomy with esophagogastrostomy was done. Microscopically it was composed of sarcomatous component intermingled with squamous cell carcinoma. Immunohistochemical stains reveal cytokeratin, 34betaE12, and p63 positivity in the nests of carcinoma, and desmin and vimentin positivity in the spindle cells of sarcomatous stoma.
