A Clinical Study on the Efficacy of Cosmetics Containing the Ascidian tunic in Reducing Wrinkles.
- Author:
Hyun Chul SUNG
1
;
Hong Dae JUNG
;
Kyung Duck PARK
;
Weon Ju LEE
;
Seok Jong LEE
;
Do Won KIM
;
Jong Taek JEON
;
Young Ju KIM
Author Information
1. Department of Dermatology, Kyungpook National University School of Medicine, Daegu, Korea. weonju@knu.ac.kr
- Publication Type:Original Article
- Keywords:
Ascidian tunic;
Cosmetic;
Wrinkle
- MeSH:
Aged;
Aging;
Cosmetics;
Fungi;
Humans;
Sebum;
Skin;
Urochordata
- From:Korean Journal of Dermatology
2008;46(7):896-902
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: In the last few decades, there has been a substantial increase in the population of aged people. Aging skin is a common concern for many people these days. OBJECTIVE: The purpose of this study was to evaluate the efficacy of cosmetics containing Ascidian tunic in reducing wrinkles. METHODS: Cream containing the Ascidian tunic was applied to right lateral epicanthal areas of 30 subjects for 8 weeks. As control group, a placebo which does not contain the Ascidian tunic was applied to the left lateral epicanthal areas of the subjects. Skin barrier function was evaluated and skin replicas were molded on both epicanthal areas every 4 weeks. The changes of the skin wrinkles were analyzed with skin visiometer. RESULTS: In comparison of the changes between groups treated with placebo and Ascidian tunic, there was statistically significant differences in hydration and sebum secretion. But there were no statistically significant differences in the result of R-value by visiometer. CONCLUSION: The treatment of Ascidian tunic extract seems to be partially effective in improving wrinkles, but further study is required.
