Effect of multiple moxibustion on platelet aggregation, blood coagulation and fibrinolytic activity in mice.
10.3777/jjsam.37.279
- VernacularTitle:マウス血小板凝集および凝固線溶能に及ぼす間けつ的連続施灸刺激の影響
- Author:
Masako OKAZAKI
;
Mayumi YAMAUCHI
;
Takako KASAHARA
;
Kouji SAKAMOTO
;
Eiji FURUYA
;
Hideharu SAKAMOTO
- Publication Type:Journal Article
- From:Journal of the Japan Society of Acupuncture and Moxibustion
1987;37(4):279-284
- CountryJapan
- Language:Japanese
-
Abstract:
Effects of multiple moxibustion on platelet aggregation, blood coagulation and fibrinolytic activity in mice have been studied. Male ddY mice (5 weeks old) were used as experimental animals. 15mg of moxa was divided into 6 cones and mice were treated by each 3 cones at right and left LV-14. The experimental schedules of multiple moxibustions were 5, 10 and 15 treatments of twice a week. The electronic aggregometer was suitable for measuring platelet aggregation using whole blood. However, no significant changes on platelet counts, platelet aggregation and ATP release induced by collagen (final concentration: 2μg/ml) and ADP (final concentration: 20μM) were found after multiple moxibustions. 15 treatments of moxibustion induced the increase in fibrinogen contents and the decrease tendency of factor XIII activity. While 10 treatments of moxibustion showed the increase in PLG content and α2 PI activity. These results suggested that multiple moxibustions induce the reasonable reaction to keep a good homeostasis on blood coagulation and fibrinolytic system in mice.
