Effect of moxibustion on aged rats. (Report 3). Reversal from movement disorders of aged animals. (2).
10.3777/jjsam.37.159
- VernacularTitle:加齢現象に及ぼす施灸刺激の影響（第３報） ラット運動失調回復における効果（２）
- Author:
Hideharu SAKAMOTO
- Publication Type:Journal Article
- Keywords:
L-DOPA
- From:Journal of the Japan Society of Acupuncture and Moxibustion
1987;37(3):159-163
- CountryJapan
- Language:Japanese
-
Abstract:
In order to studying the action mechanism of moxibustion from a viewpoint of the spontaneous movement, an experiment was attempted to ascertain whether movement dysfunctions of aged rats were able to rejuvenated by multiple moxibustion.
According to the method by Marshall (1979) measured swim performance. Female Wistar rat were used as experimental animals. Since month ago from the beginning of measurement, 15mg of moxa was divided into 6 cones and they were treated by 2 cones at right GB-25, left GB-25 and GV-20 every other week. L-Dopa methyl ester HCl (Sigma, 100mg/Kg) injected intraperitoneally or vehicle (0.9% NaCl) were given 15 minutes before being placed in the water.
The swimming of rats 10months old was compared with that of 6 month old rats.
L-Dopa rejuvenated the swimming of 10 month-old rats more vigorously and successfully than vehicle-treated. For both measure of swim performance moxibustion receiving animals also improved movement dysfunctions as well as L-Dopa receiving.
It is suggested that moxibustions stimulant appears to be rejuvenated movement dysfunctions in 10 month-old rats.
