Effect of single moxibustion stimulation on blood coagulation and fibrinolytic activities in mice. A study of AT III and fibrinolytic activities.
10.3777/jjsam.35.111
- VernacularTitle:マウス血液凝固線溶能に及ぼす１回施きゅう刺激の影響 アンチトロンビＩＩＩおよび線溶能の検討
- Author:
Eiji FURUYA
;
Kuniko OHTUKA
;
Takako KASAHARA
;
Koji SAKAMOTO
- Publication Type:Journal Article
- From:Journal of the Japan Society of Acupuncture and Moxibustion
1985;35(2):111-116
- CountryJapan
- Language:Japanese
-
Abstract:
In our previous studies, it was suggested that single moxibustion stimulation activated blood coagulation and fibrinolytic activities within normal range in mice at 1 and 3hrs.
In order to further investigate the mechanism of moxibustion, we have examined the antithrombin III (AT III) and fibrinolytic activities after single moxibustion.
Male ddy mice (6 weeks old) were used as experimental animals. Each mouse was treated with 15mg of moxa divided into 6 cones, 3 each on the right and left LV-14.
We obtained the following results. The plasminogen (PLG) activities and the values of plasma total protein decreased at 1hr after single moxibustion.
The activities of plasma AT III, α2 plasmin inhibitor (α2 PI) and factor XIII, and plasma fibrinogen level remained unchanged at 1 and 3hrs.
The blood coagulation and fibrinolytic activities changed, but they were almost within the range of physiological variability.
These results suggest that blood coagulation and fibrinolysis were activated as part of its defence mechanism while keeping homeostatic balance.
