The mechanism of the autonomic nervous system in acupuncture-stimulated bradycardia.
10.3777/jjsam.34.201
- VernacularTitle:はり刺激による心拍数減少反応の自律神経機序
- Author:
Kazuhiro YAZAWA
;
Kazushi NISHIJO
- Publication Type:Journal Article
- From:Journal of the Japan Society of Acupuncture and Moxibustion
1985;34(3-4):201-206
- CountryJapan
- Language:Japanese
-
Abstract:
Purpose
The transient decrease in heart rate occurring in response to acupuncture stimulation is a rapid reaction observed immediately after the stimulation. The reaction is considered to occur via some autonomic nervous pathway. The relationship between the decrease in heart rate due to acupuncture stimulation and the autonomic nervous system was studied based on Tanaka et al.'s test of the autonomic nervous functions.
Methods
Heart rate is, physiologically, determined by acceleration by the sympathetic nervous system, the, β-stimulator particularly, and control of inhibition achieved through the parasympathetic nerve (vagus nerve) as well as by automatism of the heart. On the basis of this fact, the vagus nerve and the β-stimulator system of the sympathetic nerve were blocked with a large amount of atropine sulfate (0.04mg/kg) and propranolol hydrochloride (0.2mg/kg) to observe the effects of acupuncture stimulation on changes in heart rate, and to study the role of each autonomic nervous system.
Results
The group in which administration of atropine sulfate preceded that of propranolol hydrochloride: After acupuncture stimulation before drug administration the heart rate definitely decreased, but the degree of decrease brought about by stimulation after administration of atropine was clearly lower than that before administration. The reaction caused by acupuncture stimulation was controlled by administration of propranolol following administration of atropine.
The group in which administration of propranolol preceded that of atropine: Heart rate was decreased by acupuncture stimulation before drug administration. The degree of decrease after administration of propranolol was lower than that before administration. When atropine was additionally administered, the decrease caused by the stimulation was controlled.
From these results of administration in the two groups, it was revealed that the decrease in heart rate caused by acupuncture stimulation occurred via excitement of the vagus nerve and control by the β-stimulator system of the sympathetic nerves.
