Study on preparation of isosorbide dinitrate in conditions of Vietnam
- Author:
Truong -- Phuong
- Publication Type:Journal Article
- Keywords:
Isosorbide dinitrate
- MeSH:
Isosorbide Dinitrate;
Sorbitol
- From:Pharmaceutical Journal
2005;347(3):20-25
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Using sorbitol - a cheap and easy-to-find material in Vietnam, the authors built a relative optimal and complete protocol to synthesize isosorbide and isosorbide dinitrate (productivity of 64%). Test purity isosorbide dinitrate and solution of 25% isosorbide dinitrate. With purity isosorbite dinitrate: qualitative analysis by IR and test by HPLC method were conducted; isosorbide dinitrate solution was test according to USP 24 and checked by this standard. All products meet USP 24 standard
