Study on preparations of sustained release propranolol tablets
- Author:
Tu Minh Koong
- Publication Type:Journal Article
- Keywords:
Propranolol tablet
- MeSH:
Propranolol;
Delayed-Action Preparations
- From:Pharmaceutical Journal
2005;347(3):5-8
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Study on the influence of appropriate sustained-release excipients on the release of propranolol hydrochloride from experimental sustained-release tablet. Hydroxyl propyl methyl cellulose and Avicel PH 101 could protect the release of propranolol hydrochloride from sustained-release tablet. Establish the coating with 2 types of polymers HPMC and Eudragit L100. Test the degree of dissolution during 12 hours and compare to the reference tablet. The release of propranolol hydrochloride from sustained release tablet prepared by the formula 20th was similar to that of reference tablet, the coefficient of f2=64.54. At the same time, the quantitative method of serum propranolol was established, in order to assess the in vivo ability of products
