The Most Important Factors for Retinopathy of Prematurity in Preterm Infants.
10.14734/kjp.2014.25.3.153
- Author:
Ji Yeon CHOI
1
;
Young Ik HAN
;
Ji Hee KIM
;
Eun Sun KIM
;
Jihyun JEON
Author Information
1. Department of Pediatrics, Bundang CHA Medical Center, CHA University School of Medicine, Seongnam, Korea.
- Publication Type:Original Article
- Keywords:
Retinopathy of prematurity;
Risk factor;
Oxygen;
Enteral feeding;
Steroid
- MeSH:
Birth Weight;
Enteral Nutrition;
Gestational Age;
Humans;
Incidence;
Infant;
Infant, Newborn;
Infant, Premature*;
Intensive Care, Neonatal;
Medical Records;
Oxygen;
Retinopathy of Prematurity*;
Retrospective Studies;
Risk Factors;
Seoul
- From:Korean Journal of Perinatology
2014;25(3):153-158
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: There are many known risk factors for a retinopathy of prematurity (ROP). We analyzed the most important risk factors and predictors of ROP among them. METHODS: We retrospectively reviewed the medical records of all premature infants admitted to the neonatal intensive care unit (NICU), between January 2010 and December 2012 at Gangnam CHA Medical Center, Seoul. . All infants (n=185) were hospitalized for more than 28 days, received eye examination for ROP and showed one of the following criteria: birth weight (BW) below 1,500 g, gestational age (GA) below 32 weeks, or oxygen treatment (> or =40% oxygen for more than 3 days). We divided the infants into the Non-ROP group (n=162) and the ROP group (n=23, more than stage 1) and analyzed group comparisons, risk factors and the importance of each factor of ROP by SPSS 13.0. RESULTS: Risk factors were duration of oxygen uses [Odds ratio (OR): 1.064, 95% confidence interval (CI): 1.007-1.125, P=0.028] and intravenous (IV) steroid (OR: 1.234, 95% CI: 1.000-1.523, P=0.049) by multi-factor adjustment. The most important factor was oxygenation duration. The following factors were time to full enteral feedings, and IV steroid duration. CONCLUSION: The incidence of ROP will be decreased if we can reduce the length of oxygen uses, IV steroid use and advance the full feeding achievement.
