A Case of Primary Adrenal Diffuse Large B-cell Lymphoma Achieving Complete Remission with Rituximab-CHOP Chemotherapy.
10.3346/jkms.2009.24.3.525
- Author:
Kyung Min KIM
1
;
Dok Hyun YOON
;
Seung Geun LEE
;
Sung Nam LIM
;
Lyu Jin SUG
;
Jooryung HUH
;
Cheolwon SUH
Author Information
1. Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. csuh@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Primary Adrenal Lymphoma;
Lymphoma, Large B-Cell, Diffuse;
R-CHOP;
Complete Remission
- MeSH:
Adrenal Gland Neoplasms/*drug therapy/pathology/radiography;
Antibodies, Monoclonal/*therapeutic use;
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use;
Cyclophosphamide/therapeutic use;
Doxorubicin/therapeutic use;
Drug Therapy, Combination;
Humans;
Lymphoma, Large B-Cell, Diffuse/*drug therapy/pathology/radiography;
Male;
Middle Aged;
Positron-Emission Tomography;
Prednisone/therapeutic use;
Tomography, X-Ray Computed;
Vincristine/therapeutic use
- From:Journal of Korean Medical Science
2009;24(3):525-528
- CountryRepublic of Korea
- Language:English
-
Abstract:
Primary adrenal lymphoma is a very rare extranodal lymphoma; its clinical features consist of a high incidence of bilateral adrenal involvement and diffuse large B-cell lymphoma. We report a patient with primary bilateral adrenal diffuse large B-cell lyphoma who achieved complete remission with R-CHOP (rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisone) chemotherapy. A 52-yr-old man presented with fever and progressive fatigue for 3 months. Computed tomography (CT) scans of the abdomen and pelvis demonstrated large bilateral adrenal masses, and a needle biopsy of the left adrenal mass revealed diffuse large B-cell lymphoma. After 6 cycles of R-CHOP chemotherapy, CT scans showed no residual disease. To our knowledge, this is the second report to date of a patient with primary bilateral adrenal diffuse large B-cell lymphoma who achieved complete remission using R-CHOP chemotherapy.
