Study of Electro-Acupuncture Therapy (muscle-EAT) for Adjuvant-Induced Arthritis in Rats
10.3937/kampomed.57.437
- VernacularTitle:アジュバント関節炎ラットに対する低周波置鍼療法（筋パルス）の検討
- Author:
Izuru MATSUHATA
;
Norimasa TANIGUCHI
;
Shigeyuki KANAI
- Publication Type:Journal Article
- Keywords:
adjuvant-induced arthritis (AA);
muscle electro-acupuncture therapy (muscle-EAT);
blood flow;
locomotor activity;
pain-related score
- From:Kampo Medicine
2006;57(4):437-441
- CountryJapan
- Language:Japanese
-
Abstract:
To examine the effectiveness of pain relief for muscle electro-acupuncture therapy (muscle-EAT), we performed a study using rats, with the adjuvant-induced arthritis (AA) rat as an experimental arthritis model. Twenty-four female SD rats (6 weeks) were divided into three groups. AA rats were raised for 8 weeks as chronic pain model. Group I (AA-E) received stimulation of the quadriceps (depth 5mm) with muscle-EAT 1 HA 10 minutes, for five days. Group II (AA-N) was untreated as controls. Group III (CTL) were the normal rat controls.
After muscle-EAT stimulation, we measured the blood flow volume in the rat foot, reactive speed response to pain-related scores, and the amount of locomotor activity. The AA group showed significantly lower blood volume and locomotor activity response than the CTL group.
Moreover, sensory abnormalities caused a delayed reactive speed to heat stimulation. After muscle-EAT stimulation, Group I showed increased blood flow volume in the foot, locomotor activity and reactive speed response in pain-related scores, compared with those shown by Group II. These findings suggest that muscle-EAT is effective for relief of pain induced by chronic inflammation.
