A Case of Focal Glomerular Sclerosis (Glomeruloscrelosis) Treated with Bunsho-to.
10.3937/kampomed.52.325
- VernacularTitle:分消湯が奏効した巣状糸球体硬化症によるネフローゼ症候群の一症例
- Author:
Naotoshi SHIBAHARA
;
Nobuyasu SEKIYA
;
Kiyoaki TANIKAWA
;
Yuji KASAHARA
;
Yutaka SHIMADA
;
Takashi ITOH
;
Katsutoshi TERASAWA
- Publication Type:Journal Article
- Keywords:
Focal glomerular sclerosis;
Bunsho-to;
Steroid-dependent nephrotic syndrome;
Kampo treatment
- From:Kampo Medicine
2001;52(3):325-333
- CountryJapan
- Language:Japanese
-
Abstract:
We report a case of a patient with steroid-dependent nephrotic syndrome, who achieved complete remission with a combination of steroid therapy and Bunsho-to. The patient was a 27-year-old female who became aware of edema, and was diagnosed as suffering from focal glomerular sclerosis (glomerulosclerosis) with nephrotic syndrome in November 1992. She responded to steroid therapy, but nephrotic syndrome relapsed frequently after the repeated reduction of steroids. In July 1995, she came to our hospital, and was diagnosed as having a recurrence of nephrotic syndrome. Although the combination therapy of steroid and Kampo formulas, Shinbu-to or Shimotsu-to and/or Keigairengyo-to, was effective, an exacerbation of nephrotic syndrome occurred after steroid therapy was discontinued, in July 1997. The prescription was changed to Bunsho-to, and steroid therapy was re-initiated with 10mg of prednisolone daily. As a result, she achieved complete remission. The steroid therapy could be discontinued in July 1999, and now she has taken Bunsho-to only for 18 months. But the complete remission of nephrotic syndrome has been maintained.
