Three Cases in which Symptom-Producing doses of Kampo Medicine with Aconiti Tuber Dramatically Ameliorated Primary Diseases.
10.3937/kampomed.50.247
- VernacularTitle:烏頭含有方剤による中毒症状とともに劇的に改善した三症例
- Author:
Kazufumi KOHTA
;
Tadamichi MITSUMA
;
Takuhiro SHINTANI
;
Takashi ITOH
;
Katsutoshi TERASAWA
- Publication Type:Journal Article
- Keywords:
aconiti tuber;
intoxication;
Mengen (unexpected reaction)
- From:Kampo Medicine
1999;50(2):247-255
- CountryJapan
- Language:Japanese
-
Abstract:
Recently we observed three cases in which symptom-producing doses of Kampo medicine with aconiti tuber dramatically ameliorated primary diseases. The symptoms were similar to intoxication caused by aconiti tuber. Case 1 had been suffering from rheumatoid arthritis. After the daily dose of Keishi-ni-eppi-itto-ka-ryojutsubu, a Chinese herbal medicine containing aconiti tuber, was increased from 6g/day to 7g/day, the patient briefly experienced palpitation and nausea. At the same time, polyarthralgia and laboratory data dramatically improved. Case 2 suffered from lumbago due to osteoarthritis. Numbness around the lips and in the limbs and gait disturbance occurred in this patient after the basal prescription was changed from Shakuyaku-kanzo-bushi-to to Hachimijio-gan-ryo with the 4g/day dose of aconiti tuber remaining the same. The patient's lumbago disappeared almost completely. Case 3 had osteoarthritis and began taking Hachimijio-gan-ryo, containing aconiti tuber (8g/day), in early June. Numbness around the lips and limbs occurred after administration of Hachimijio-gan-ryo containing aconiti tuber (4g/day) in late July. After that, her gonalgia was recovered. Based on our experience above, we had the impression as follows: 1) Symptoms similar to intoxication due to aconiti tuber may be caused not only by increasing the daily dose of aconiti tuber, but also by changes of basal description or climate variations such as a rise in temperature. 2) In order to use aconiti tuber effectively, it is sometimes necessary to increase the daily dose to the level where it provides treatment, in spite of the risk of intoxication.
