Treatment of Hypertriglyceridemia Using Herbs.
10.3937/kampomed.50.235
- VernacularTitle:胆道排石湯加減方による高中性脂肪血症の治療
- Author:
Yasuyo HIJIKATA
;
Hiroshi MIURA
;
Xi Lu
- Publication Type:Journal Article
- Keywords:
hyperlipidemia;
triglyceride;
(modified) Dandao-paishi-tang
- From:Kampo Medicine
1999;50(2):235-240
- CountryJapan
- Language:Japanese
-
Abstract:
HMG-CoA reductase inhibitor, routinely utilized in the treatment of hypertriglyceridemia, does not decrease serum levels of triglyceride (TG) as much as it decreases levels of cholesterol. Clofibrates, on the other hand, quite effectively decrease triglyceride levels but severe adverse effects have been reported. Dandao-paishi-tang, a Chinese herb combination, generally used to promote the passage of gallstones, was modified and used to treat three patients with hypertriglyceridemia. A male with hypertriglyceridemia, mild hypertension, and cholelithiasis began to take modified Dandao-paishi-tang when 55 years old. Serum TG level decreased from 634mg/dl to 273mg/dl over four years of treatment. A 66-year-old female patient with hypertriglyceridemia and diabetes took the prescription for four months and TG decreased from 815mg/dl to 442mg/dl. A 76-year-old female with mild hypertriglyceridemia showed a decrease in TG from 154mg/dl to 132mg/dl in four months.
