Effects of Kampo Medicine Extracts on the Arthritis Score and Histological Change of Synovitis in Adjuvant-Induced Arthritis in Rats. (I).
10.3937/kampomed.49.419
- VernacularTitle:ラット・アジュバント関節炎における漢方薬の作用 関節腫脹率及び病理組織に対する漢方薬の作用 （第１報）
- Author:
Fang TANG
;
Yucca NAKANISHI
;
Machiko ORITA
;
Hiroko ABE
- Publication Type:Journal Article
- Keywords:
adjuvant-induced arthritis;
rats;
synovitis;
Chinese medicine (Sokei-kakketsu-to, Yokuinin-to, Keisi-ka-jutsubu-to, Eppi-ka-jutsu-to, Sairei-to)
- From:Kampo Medicine
1998;49(3):419-428
- CountryJapan
- Language:Japanese
-
Abstract:
The effects of Sokei-kakketsu-to, Yokuinin-to, Keisi-ka-zyutsubu-to, Eppi-ka-jutsu-to, and Saireito extracts on Adjuvant-induced arthritis (AA) in rats were investigated. After administering AA, we measured the volume of rat hindpaw as the inflammation index, and observed the changes of synovitis histologically. Each extract showed different effects on AA rats. Yokuinin-to and Sokei-kakketsu-to had remarkable effects on inflammation and changed the histological observations of synovitis. Eppi-ka-jutsu-to also had effects on the uninjected hindpaw, but Keisi-ka-jutsubu-to and Sairei-to had no effect on hindpaw inflammation, nor did they change synovitis histologically.
