A Case of Thrombocytopenia arising from Systemic Lupus Erythematosus Effectively Treated with Juzen-Taiho-To.
10.3937/kampomed.48.327
- VernacularTitle:全身性エリテマトーデスの難治性血小板減少症に十全大補湯が奏効した一例
- Author:
Hiroaki HIKIAMI
;
Toshiaki KOGURE
;
Toshiaki KITA
;
Yutaka SHIMADA
;
Katsutoshi TERASAWA
- Publication Type:Journal Article
- Keywords:
Systemic Lupus Erythematosus;
Thrombocytopenia;
Juzen-taiho-to
- From:Kampo Medicine
1997;48(3):327-333
- CountryJapan
- Language:Japanese
-
Abstract:
A patient with systemic lupus erythematosus (SLE), complicated by severe thrombocytopenia was successfully treated with Juzen-taiho-to. The patient was a 38-year-old woman presenting thrombocytopenia in 1974. She was diagnosed as having SLE with the appearance of renal failure in 1975. In 1984, she began blood dialysis due to deterioration of renal function. In addition, she repeatedly suffered from severe bleeding episodes due to thrombocytopenia. In 1989, she visited our clinic to undergo Kampo therapy, with no significant results obtained with any of the formulas tried.
In September 1992, she suffered from duodenal ulcer bleeding and stopped Kampo therapy for some time. However, since she began taking Juzen-taiho-to in June 1993, her thrombocytopenia improved and her platelet count stabilized at 10-15×104/mm3. This made it possible to taper the dosage of the steroids being administered. Since July 1994, the prednisolone (PSL) dosage has been 5mg on alternate days. Since July 1995, the anti-DNA antibody was negative. The platelet count has been maintained at 15-20×104/mm3 (as of December, 1996).
