Effects of Kampo Medicine Extracts on Morphological Changes in the Small Intestinal Mucosa of Mice with Age.
10.3937/kampomed.48.7
- VernacularTitle:加齢に伴うマウスの小腸粘膜の変化に対する漢方薬の作用 六君子湯,補中益気湯,人参養栄湯,半夏しゃ心湯エキス剤の作用
- Author:
Fang TANG
;
Yuka NAKANISHI
;
Atsushi NAKANO
;
Hiroko ABE
- Publication Type:Journal Article
- Keywords:
aging small intesinal mucosa;
morphological changes;
Chinese medicine;
mice;
Rikkunshi-to;
Hochu-ekki-to;
Ninjin-yoei-to;
Hange-shashi-to
- From:Kampo Medicine
1997;48(1):7-15
- CountryJapan
- Language:Japanese
-
Abstract:
The effects of Rikkunshi-to (Liu jun zi tang), Hochu-ekki-to (Bu zhong yi qi tang), and Hange-shashin-to (Ban xia xie xin tang) on morphological changes in the small intestinal mucosa of mice with age were observed. The results indicated that Rikkunshi-to and Hochu-ekki-to had a beneficial effect on intestinal mucosal changes in 36-weeks-old mice. In particular, the improvement of the absorptive area of the intestinal villi and microvilli depending on the concentration of medicine was found. Ninjin-yoei-to had a strong effect on aged mice of 50 and 70 weeks. The morphology and absorptive function were significantly improved.