A Trial Study of Kikyo-to on Abdominal Symptoms in Chronic Pancreatitis Patient.
10.3937/kampomed.48.31
- VernacularTitle:桔梗湯の慢性すい炎症例に伴う腹部症状に対する治療効果の基礎的および臨床的検討
- Author:
Ichiro ARAI
;
Yasuhiro KOMATSU
;
Hisashi YAMAURA
;
Susumu TAGUCHI
- Publication Type:Journal Article
- Keywords:
Kikyo-to;
chronic pancreatitis;
abdominal symptoms;
cholecystokinin;
secretin
- From:Kampo Medicine
1997;48(1):31-36
- CountryJapan
- Language:Japanese
-
Abstract:
The authors investigated the activity of Kikyo-to on the intestinal hormones, cholecystokinin (CCK) and secretin, released in healthy humans. The clinical efficacy of Kikyo-to on the abdominal symptoms associated with chronic pancreatitis was also investigated. In healthy volunteers, Kikyo-to (5g) significantly increased plasma CCK and secretin concentrations 30 minutes after treatment. In chronic pancreatitis patients, abdominal pain, abdominal tenderness, nausea and diarrhea were decreased by treatment with Kikyo-to (7.5g/day; divided into three doses). In conclusion, Kikyo-to improved the complaints of chronic pancreatitis, especially abdominal pain. The presumed mechanism was that Kikyo-to stimulated pancreatic exocrine secretion by the release of intestinal hormones, CCK and secretin.
