Effective Treatment of a Case of Chronic Renal Failure Complicated by Nephrotic Syndrome with Hochu-Ekki-To and Keishi-Bukuryo-Gan-Ka-KokaDaio.
10.3937/kampomed.47.43
- VernacularTitle:補中益気湯と桂枝ぶく苓丸加紅花大黄が奏効したネフローゼ症候群を呈した慢性腎不全の一例
- Author:
Toshiaki KOGURE
;
Hiroaki HIKIAMI
;
Yutaka SHIMADA
;
Takashi ITOH
;
Katsutoshi TERASAWA
- Publication Type:Journal Article
- Keywords:
Keishibukuryo-gan-ka kokadaio;
acute exacerbation of chronic renal failure;
nephrosis
- From:Kampo Medicine
1996;47(1):43-48
- CountryJapan
- Language:Japanese
-
Abstract:
The authors would like to report the successful treatment with Hochuekki-to and Keishibukuryo-gan of a case of chronic renal failure that had deteriorated rapidly in a short period of time.
The patient was a 29-year-old woman that had been diagnosed as having IgA renal syndrome in 1987 after a local physician had detected proteinuria and requested a renal biopsy. In November of the same year she came to the authors' clinic requesting Kampo therapy. After her kidney function was stabilized with such formulas as Gorei-san and Byakokaninjin-to, the patient stopped coming to the clinic. In February of 1992, she returned to the clinic with renal failure following an episode of acute pneumonia. She was admitted to the hospital due to hypertension (Cr 2.8mg/dl; BUN 20mg/dl). Dietary therapy and hypertension control were carried out, and administration of 40mg/day of prednisone (PSL) was commenced on the 10th day following admittance. Since the proteinuria remained unchanged, 1g/day of methyl-PSL was given for three days from the 18th day after admittance. However, by the 38th day (4 weeks after commencement of PSL administration) the Cr was 5.0mg/dl. At this point the Kampo formula was changed from Sairei-to to Hochuekki-to in conjunction with Keishibukuryo-gan-ka-kokadaio. Her kidney function began to improve, and by the 108th day the laboratory findings had decreased to Cr 2.7mg/dl and Bun 26mg/dl and the PSL dosage was reduced to 20mg/day. She was discharged from the hospital on the 110th day, and has been progressing well as an out-patient.
