Giant malignant insulinoma.
10.4174/astr.2015.88.5.289
- Author:
Dimitrios KARAVIAS
1
;
Ioannis HABEOS
;
Ioannis MAROULIS
;
Christina KALOGEROPOULOU
;
Athanasios TSAMANDAS
;
Ioannis CHAVELES
;
Dionissios KARAVIAS
Author Information
1. Department of Surgery, University Hospital of Patras, Rion, Greece. dimitriskaravias@gmail.com
- Publication Type:Case Report
- Keywords:
Insulinoma;
PNET;
Giant tumor
- MeSH:
Aged;
Diagnosis;
Female;
Glucose;
Humans;
Hypoglycemia;
Insulinoma*;
Kidney;
Lymph Nodes;
Neoplasm Metastasis;
Neuroectodermal Tumors, Primitive;
Neuroendocrine Tumors
- From:Annals of Surgical Treatment and Research
2015;88(5):289-293
- CountryRepublic of Korea
- Language:English
-
Abstract:
Insulinomas are the most common pancreatic neuroendocrine tumors. Most insulinomas are benign, small, intrapancreatic solid tumors and only large tumors have a tendency for malignancy. Most patients present with symptoms of hypoglycemia that are relieved with the administration of glucose. We herein present the case of a 75-year-old woman who presented with an acute hypoglycemic episode. Subsequent laboratory and radiological studies established the diagnosis of a 17-cm malignant insulinoma, with local invasion to the left kidney, lymph node metastasis, and hepatic metastases. Patient symptoms, diagnostic and imaging work-up and surgical management of both the primary and the metastatic disease are reviewed.
