Effects of Kampo Therapy on Serum Estrogen Levels and Bone Mineral Content in Climacteric Disorder.
10.3937/kampomed.45.521
- VernacularTitle:血中エストロゲン値と骨量からみた更年期障害治療時における漢方療法の効果
- Author:
Kiyoyuki HARADA
;
Yoshinori NAKATA
- Publication Type:Journal Article
- Keywords:
Climacteric disorder;
Kampo therapy;
Serum Estrogen levels;
Bone mineral contents
- From:Kampo Medicine
1995;45(3):521-527
- CountryJapan
- Language:Japanese
-
Abstract:
Serum estrogen levels and bone mineral contents were measured to study their changes during treatment of climacteric disorder with Kampo therapy.
Sixty-five patients who visited the outpatient department of climacteric hormones received either (1) estrogen, (2) Kampo therapy (Saiko-ka-ryukotsu-borei-to, Keishi-bukuryo-gan, or Tokaku-joki-to) or (3) a calcium preparation alone or only psychological therapy (no drug treatment), for six months. Group (3) was treated as the control. Serum E2 levels, bone mineral contents, and cortical bone width index, etc., were determined before and after treatment.
In patients treated with Saiko-ka-ryukotsu-borei-to, blood E2 levels increased. In patients treated with Saiko-ka-ryukotsu-borei-to or Tokaku-joki-to, reductions in bone mineral content and the cortical bone width index were suppressed. We therefore concluded that Saiko-ka-ryukotsu-borei-to is effective in preventing osteoporosis. This study also suggests that a combination of Kampo therapy and a calcium preparation may be highly beneficial in preventing menopausal osteoporosis.
