Effect of Regression toward the Mean in Evaluating the Efficacy of Kampo Prescriptions. Analysis with AIC.
10.3937/kampomed.43.413
- VernacularTitle:漢方処方の薬効評価における平均への回帰による影響 赤池情報量規準（ＡＩＣ）による解析
- Author:
Akifumi YAFUNE
- Publication Type:Journal Article
- Keywords:
Regression toward the mean;
Akaike Information Criterion;
Evaluation of the efficacy of Kampo prescriptions
- From:Kampo Medicine
1993;43(3):413-420
- CountryJapan
- Language:Japanese
-
Abstract:
In many clinical studies to evaluate the efficacy of Kampo prescriptions, subjects are selected because they have high or low values of the characteristics of interest, such as blood pressure or serum cholesterol, and the data obtained from the subjects before and after treatment are analyzed. In such analyses, we should take into account the possible changes in the observations due to regression toward the mean, otherwise the results of the analyses will be incorrect.
In this paper, we consider the effect of regression toward the mean in analyzing data and propose a method of analysis with Akaike Information Criterion (AIC) to avoid incorrect results.
