Russell Body - Containing Plasma Cell Aggregations Mimiccking Signet Ring Cell Carcinoma of the Stomach.
- Author:
Eun Sil YU
;
Yong Il KIM
;
Chul Woo KIM
;
Woo Ho KIM
- Publication Type:Original Article
- MeSH:
Biopsy;
Carcinoma, Signet Ring Cell*;
Diagnosis, Differential;
Eosinophils;
Female;
Humans;
Mucous Membrane;
Peptic Ulcer;
Plasma Cells*;
Plasma*;
Stomach Ulcer;
Stomach*;
Ulcer
- From:Korean Journal of Gastrointestinal Endoscopy
1987;7(1):39-41
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This report presents a case with gastric ulcer whose gastric mucosal biopsy revealed heavy aggregations of Russell body containing plasma cells in the lamina propria and in peptic detritus. A sixty four year old female received an endoscopic examination for currently aggravated peptic ulcer symytoms, It revealed a small round ulcer with nodular margin along the greater curvature of high body, suggesting of early gastric carcinoma. Endoscopic biopsies (two times) confirmed heavy collections of Russell body-containing plasma cells which were once misinterpreted as signet ring cell carcinoma. Immonohistochemically they were strongly positive to both kappa and lambda light chains by pgtroxidase-antiperoxidase method. Each infiltrated cell contained one or more refractile intracytoplasmic eosinophilic globules, bcing associated with extracellular ones and heavy matare lympho-plasma cell infiltration. Differential diagnosis from neoplastic signet ring cells in endoscopic biopsy was diseussed.
