A Case of Coronary Artery Bypass Grafting with Essential Thrombocythemia
10.4326/jjcvs.36.342
- VernacularTitle:本態性血小板血症を合併した多枝冠動脈バイパス術の１例
- Author:
Satoshi Hamada
;
Yoshinori Watanabe
;
Noritsugu Shiono
;
Muneyasu Kawasaki
;
Takeshirou Fujii
;
Tsukasa Ozawa
;
Hiroshi Masuhara
;
Nobuya Koyama
- Publication Type:Journal Article
- From:Japanese Journal of Cardiovascular Surgery
2007;36(6):342-344
- CountryJapan
- Language:Japanese
-
Abstract:
We experienced the coronary artery bypass grafting (CABG) with essential thrombocythemia (ET). A case is a man of 73 years old. As for him, 3 vessel disease including left main trunk was recognized on coronary angiography, and it was planned CABG. However, we recognized blood cell aberration in blood examination, and it was diagnosed as ET. ET is classed as a chronic myeloproliferative disorder. It has two opposite tendencies, a bleeding tendency and thrombus tendency. Ischemic heart disease to merge ET is acute myocardial infarction by thrombus in case of most, and there are a few cases to need blood circulation reconstruction of coronary artery for angina pectoris. Perioperative hemorrhage and postoperative graft closure become a problem in CABG with ET. With the hydroxycarbamide which is DNA synthesis inhibitor of a platelet count, a function controlled it, and enforced CABG. He doesn't have any cardiac events and complications due to ET for 7 years post CABG. We report this case with a review of the literature.
