Gene disorders and the treatment for genes
- Author:
Vu Trieu An
- Publication Type:Journal Article
- Keywords:
Genes
- MeSH:
Genes;
Therapeutics;
Disease
- From:Journal of Medical Research
2004;27(1):147-154
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
With the progress of molecular biology and the mapping of total human genome, treatment of monogene diseases by the method of gene engineering was possible as preliminary achieved success, but there were still unsolved problems. The most difficult problem had been that the insert of a healthy gene into a modified cell could product a deficit protein, but what is the mechanism of controlling and regulating its activity because homeostatic equilibrium is an important principle of a living body. This principle will not be assured when a gene activated without an equilibrium mechanism. When the new gene begins to activate, an other condition will be occurred, for instance an access of the previously deficit protein, i.e. an artificial cancer
