Aortic Root Replacement with a Freestyle Porcine Valve in a Young Woman with Systemic Lupus Erythematosus and Antiphospholipid Antibodies
10.4326/jjcvs.34.194
- VernacularTitle:抗リン脂質抗体陽性全身性エリテマトーデスに合併したａｏｒｔｉｃ ｒｏｏｔ ａｎｅｕｒｙｓｍに対しＦｒｅｅｓｔｙｌｅ人工弁にて大動脈基部再建を施行した若年女性の１例
- Author:
Harumasa Yasuda
;
Nobuo Sakagoshi
- Publication Type:Journal Article
- Keywords:
SLE;
aortic root aneurysm
- From:Japanese Journal of Cardiovascular Surgery
2005;34(3):194-197
- CountryJapan
- Language:Japanese
-
Abstract:
Aortic root replacement with a FreestyleTM stentless porcine valve (Medtronic Inc.) was performed on a 32-year-old woman for aortic root aneurysm. The patient had been given a diagnosis of systemic lupus erythematosus and had been maintained on steroid therapy for 15 years. Lupus anticoagulant was present and the anticardiolipin antibody titer was abnormal as follows: IgG, 2.0IU/ml (normal<1.0IU/ml). For the patient requiring aortic root reconstruction, many options are available. The use of a biological valved conduit should be considered for patients in whom anticoagulation is not desirable. The FreestyleTM stentless porcine valve offers an acceptable alternative to mechanical prostheses, especially for cases with contraindication for anticoagulant therapy, associated with antiphospholipid antibodies.
