A Case of Aortic Valve Replacement in Patient with Chronic Idiopathic Thrombocytopenic Purpura.
10.4326/jjcvs.29.400
- VernacularTitle:特発性血小板減少性紫斑病（ＩＴＰ）を合併した大動脈弁狭窄症の手術例
- Author:
Hiroyuki Hirose
;
Motomi Shiono
;
Yukihiko Orime
;
Shinya Yagi
;
Tomonori Yamamoto
;
Haruhiko Okumura
;
Mitsumasa Hata
;
Nanao Negishi
;
Yukiyasu Sezai
;
Yoshihiro Matsukawa
- Publication Type:Journal Article
- From:Japanese Journal of Cardiovascular Surgery
2000;29(6):400-403
- CountryJapan
- Language:Japanese
-
Abstract:
A 66-year-old woman with aortic stenosis and idiopathic thrombocytopenic purpura (ITP) underwent concomitant splenectomy and aortic valve replacement (AVR). High-dose trans-venous gamma-globulin therapy (400mg/kg/day) was performed for five days before surgery. The number of platelet, which was 6.0×104/mm3 on admission slighty increased to 7.0×104/mm3 before surgery. The aortic valve was replaced by an ATS 19mm prosthesis using cardiopulmonary bypass. Platelets were transfused postoperatively. Perioperative hemorrhage was moderate, and the postoperative course was uneventful. This was the second case we treated by concomitant cardiac surgery and splenectomy. It was safely performed after high-dose trans-venous gamma-globulin therapy.
