Study on antioxidant activities and preliminary investigation on antibacterial, antifungal of extracted fraction rich in flavonoides from leaves of Pseuderanthemum palatiferum (Nees) Radlk
- Author:
Phan Minh Giang
- Publication Type:Journal Article
- Keywords:
Leaves of Pseuderanthemum palatiferum (Nees) Radlk
- MeSH:
Flavonoids;
Antioxidants;
Anti-Bacterial Agents;
Antifungal Agents
- From:Pharmaceutical Journal
2005;353(9):9-12
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Leaves of Pseuderanthemum palatiferum (Nees) Radlk., Acanthaceae, was traditionally used to treat various diseases, including digestive disorders, spastic colitis, stomach ache, traumatic bleeding, kidney and liver diseases. The extract of ethyl acetate and n-butanol soluble fractions (accounted for 1% of the dry material) were prepared from the leaves of P. palatiferum as the flavonoid-enriched fractions. The antioxidant activities of the flavonoid-enriched fractions were evaluated by their influences on the activities of the blood peroxidase. The results demonstrated that antioxidant activities of flavonoid-enriched fractions were depended on blood groups and had potent, selective effects. Moderate (of n-butanol fraction) to strong antibacterial activity (of ethyl acetate fraction) and insignificant antifungal activity (of both ethyl acetate and n-butanol fractions) against ten bacteria strains and two fungi Candida albicans and Candida stellatoides were observed using standard disc diffusion method. Strong sensitivity of Salmonella typhi 158, Shigella flexneri and Escherichia coli to the ethyl acetate fraction was noteworthy. The results showed the probable involvement of the flavonoids in the antioxidant and antibacterial activities of the ethyl acetate and n-butanol soluble fractions from the leaves of Pseuderanthemum palatiferum
