The Influence of Continuous Warm Blood Cardioplegia on Intraoperative Cardiac Aerobic Metabolism.
10.4326/jjcvs.27.11
- VernacularTitle:Ｃｏｎｔｉｎｕｏｕｓ ｗａｒｍ ｂｌｏｏｄ ｃａｒｄｉｏｐｌｅｇｉａが術中心筋好気性代謝に与える影響
- Author:
Ichiya Yamazaki
;
Tamitaro Soma
;
Takayuki Kosuge
- Publication Type:Journal Article
- Keywords:
continuous warm blood cardioplegia;
cold crystalloid cardioplegia
- From:Japanese Journal of Cardiovascular Surgery
1998;27(1):11-18
- CountryJapan
- Language:Japanese
-
Abstract:
Continuous warm blood cardioplegia (CWBC) was compared with cold crystalloid cardioplegia (CCC) with regard to intraoperative cardiac aerobic metabolism. Thirty-six adult patients who underwent CABG were divided into two groups. The CWBC group (n=21) received continuous warm blood cardioplegia while the CCC group (n=15) received 4°C St. Thomas' Hospital cardioplegic solution. Some parameters of cardiac anaerobic metabolism were measured intraoperatively. We continuously measured the oxygen saturation of coronary sinus blood (ScsO2) after aortic declamping until 5 minutes after cardiopulmonary bypass (CPB). CK and CK-MB levels were measured at admission to ICU, and on the first and second postoperative day (POD) in both groups. CPB time, aortic-cross clamp time and incidence of postoperative low output syndrome were similar in the two groups. The spontaneous return to sinus rhythm after aortic declamping was significantly higher in the CWBC group. ScsO2 was significantly higher in the CWBC group. The lactate uptake ratio of myocardium, excess lactate and redox potential were similar in the two groups. CK and CK-MB levels were significantly lower in the CWBC group. We concluded that the CWBC group was superior to the CCC group in terms ScsO2, CK and CK-MB levels. Other parameters of cardiac anaerobic metabolism were similar in the two groups.
