The Superiority of Continuous Warm Blood Cardioplegia about Postoperative Cardiac Function.
10.4326/jjcvs.26.90
- VernacularTitle:術後急性期の心機能におけるＣｏｎｔｉｎｕｏｕｓ ｗａｒｍ ｂｌｏｏｄ ｃａｒｄｉｏｐｌｅｇｉａの優位性
- Author:
Ichiya Yamazaki
;
Tamitaro Soma
;
Takayuki Kosuge
- Publication Type:Journal Article
- Keywords:
continuous warm blood cardioplegia;
cold crystalloid cardioplegia
- From:Japanese Journal of Cardiovascular Surgery
1997;26(2):90-95
- CountryJapan
- Language:Japanese
-
Abstract:
Continuous warm blood cardioplegia (CWBC) was compared with cold crystalloid cardioplegia (CCC) with regard to postoperative cardiac function. 36 adult patients underwent CABG divided into two groups. The CWBC group (n=21) received continuous warm blood cardioplegia while the CCC group (n=15) received 4°C St. Thomas' Hospital cardioplegic solution. Some parameters or cardiac function, CK and CK-MB levels were measured at admission to ICU, and on the first and second postoperative day (POD) in both groups. The amount of dopamine and dobutamine were measured at admission to ICU and 6, 12, 18, 24 hours after admission to ICU in both groups. Cardiopulmonary bypass (CPB) time, aortic-cross clamp time and incidence of postoperative low output syndrome were similar in the two groups. The spontaneous return to sinus rhythm after aortic declamping was significantly higher in the CWBC group. The cardiac index measued at admission to ICU, 1 POD and 2 POD was significantly larger in the CWBC group. Pulmonary capillary wedge pressure and right atrial pressure measured at 1 POD and 2 POD were significantly lower in the CWBC group. Systemic vascular resistance measured at admission to ICU, at 1 POD and 2 POD were significantly lower in the CWBC group. Left ventricle stroke work index and left ventricle work index measured at admission to ICU were significantly larger in the CWBC group. Right ventricle stroke work index and right ventricle work index were similar in the two groups. The amount of dopamine at admission to ICU and at 6 and 12 hours after admission to ICU were significantly lower in the CWBC group. The amounts of dobutamine at admission to ICU and at 6, 12, 18 and 24 hours after admission to ICU were significantly lower in the CWBC group. CK levels measured at admission to ICU and at 1 POD were significantly lower in the CWBC group. CK-MB levels measured at admission to ICU, 1 POD and 2 POD were significantly lower in the CWBC group.
