The Efficacy of Ultrafiltration after Cardiopulmonary Bypass without Homologous Blood Transfusion for Pediatric Cardiac Surgery.
10.4326/jjcvs.23.73
- VernacularTitle:小児無血充填体外循環における限外ろ過の効果に関する臨床的検討 2種類のhollow fiber型限外ろ過装置を用いて
- Author:
Hiroshi Watanabe
;
Haruo Miyamura
;
Masaaki Sugawara
;
Yoshiki Takahashi
;
Mayumi Shinonaga
;
Shoh Tatebe
;
Masashi Takahashi
;
Shoji Eguchi
- Publication Type:Journal Article
- From:Japanese Journal of Cardiovascular Surgery
1994;23(2):73-77
- CountryJapan
- Language:Japanese
-
Abstract:
Thirty-four patients with congenital cardiac disease were studied to evaluated the role of ultrafiltration after cardiopulmonary bypass without homologous blood transfusion. We used either polypropylene microporous hollow fiber hemoconcentrator (HC-30M or 100M) or polyacrylonitrile microporous hollow fiber hemoconcentrator (PHC-500). Ultrafiltration was useful in the reduction of fluid overloading after cardiopulmonary bypass with extreme hemodilution. Thirty-two patients tolerated the procedure uneventfully without donor blood transfusion and were discharged from the hospital. The values of hematocrit, serum protein and free hemoglobin increased significantly after ultrafiltration with either type of hemoconcentrator. However the degree of concentration of blood components was significantly higher with polyacrylonitrile hemoconcentrator than those with polypropylene hemoconcentrator. These results indicated that ultrafiltration was useful for maintaining water balance after cardiopulmonary bypass without homologous blood transfusion in pediatric cardiac surgery and that polyacrylonitrile microporous hollow fiber hemoconcentrator should be employed in patients with shorter bypass time and less hemolysis.