Two Cases of the Blue Toe Syndrome Treated by Prostaglandin E1(PGE1).
10.4326/jjcvs.22.36
- VernacularTitle:Ｐｒｏｓｔａｇｌａｎｄｉｎ Ｅ１が有効であったｂｌｕｅ ｔｏｅ ｓｙｎｄｒｏｍｅの２例
- Author:
Saihou HAYASHI
;
Yoshiharu HAMANAKA
;
Taijiro SUEDA
;
Kazumasa ORIHASHI
;
Takayuki NOMIMURA
;
Satoru MORITA
;
Tetsuya KAGAWA
;
Yuichiro MATSUURA
- Publication Type:Journal Article
- Keywords:
blue toe syndrome;
prostaglandin E1
- From:Japanese Journal of Cardiovascular Surgery
1993;22(1):36-40
- CountryJapan
- Language:Japanese
-
Abstract:
Two cases of blue toe syndrome were effectively treated by PGE1. Case 1 was an 80-year-old man who had an ulcer lesion of the 5th toe. Angiography indicated the symptoms were caused by microemboli from an extended lesion of the aorta and iliac artery. The wound was healed by lipo PGE1 (10μg×30 days). Case 2 was a 54-year-old man who had dull pain and skin color change of the 3rd and 4th fingers. A thrombus could not be detected by transthoracic echocardiography, but was found by transesophageal echocardiography. The symptoms improved by PGE1 (60μg×20days). Blue toe syndrome is induced by a microembolism in the peripheral arteries, and thus the conventional treatment has been the administration of fibrinolysins and anticoagulants. PGE1 was used in this study for the first time in consideration of its vasodilating effect on the collateral circulation and to prevent a secondary thrombus by inhibiting platelet aggregation.
