Experimental Study of Microvascular Anastomosis Using GRF Glue.
10.4326/jjcvs.22.26
- VernacularTitle:接着剤ＧＲＦを用いた微小血管吻合の実験的研究
- Author:
Katsuhiko MATSUDA
;
Nobushige TAMURA
- Publication Type:Journal Article
- Keywords:
Biological glue;
microvascular anastomosis;
GRF
- From:Japanese Journal of Cardiovascular Surgery
1993;22(1):26-29
- CountryJapan
- Language:Japanese
-
Abstract:
The GRF glue consists of mixture of gelatine and resorcine. The mixture is hardened by the addition of medical formaldehyde. Resorcine is diphenole which reacts with formaldehyde, creating tridimentional network. We performed microvascular anastomosis of abdominal aorta of the rat using GRF glue and the histologial study by the light microscope and the scanning electron microscope. Re-endoterization began from two days after anastomosis and completed at ten days to two weeks after anastomosis. From scanning electron microscopic study the invasion of macrophages and platelets in the case of anastomosis using GRF glue was less than in the case of manual or laser anastomosis. We revealed that GRF glue is very useful for bonding of micro vessels.
