Efficacy of Preoperative Dipyridamole-loaded ECG in the Assessment of Coronary Artery Disease in Arteriosclerosis Obliterans.
10.4326/jjcvs.20.1465
- VernacularTitle:閉塞性動脈硬化症(ASO)における冠動脈病変合併の評価 ジピリダモール負荷心電図法の有用性について
- Author:
Tohru YAMAZAKI
;
Akira HAKOSHIMA
;
Mikio ISHIKAWA
;
Shin ISHIMARU
;
Kin-ichi FURUKAWA
- Publication Type:Journal Article
- From:Japanese Journal of Cardiovascular Surgery
1991;20(9):1465-1469
- CountryJapan
- Language:Japanese
-
Abstract:
To assess coronary artery disease in arteriosclerosis obliterans (ASO), the efficacy of a dipyridamole-loaded ECG was evaluated. Subjects consisted of 35 patients who underwent surgery for ASO between November 1988 and December 1989. A dose of 0.568mg/kg of dipyridamole was intravenously infused for over 4min. Changes of systemic blood pressure, heart rate and standard 12-lead ECG were accumulated. In eleven cases loaded ECG was considered to be positive and coronary arteriographies were performed. Stenotic lesions of 75% or over were observed in 10 cases, among them CABG was performed in one symptomatic case. In another positive but asymptomatic cases, only the existing ASO lesions were surgically treated. No intraoperative or postoperative ECG abnormality was observed and postoperative courses were uneventful. Negative cases (24 cases) underwent complete revascularization. These findings indicate that a dipyridamole-loaded ECG is a non-invasive preoperative means detecting coronary artery disease preoperatively is useful to decide operative procedure.