Increased bone mineral density according to increase of skeletal muscle mass in 534 Korean women: A retrospective cohort study conducted over 2.7 years.
10.5468/ogs.2015.58.2.135
- Author:
Sun Mie KIM
1
;
Seok Hyun KIM
;
Jin Ju KIM
;
Min Jeong KIM
;
Hyuk Tae KWON
;
Chang Suk SUH
;
Young Min CHOI
;
Jung Gu KIM
Author Information
1. Seoul National University Hospital Health Care System Kangnam Center, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Abdominal fat;
Bone density;
Metabolic syndrome;
Skeletal muscle mass
- MeSH:
Abdominal Fat;
Absorptiometry, Photon;
Body Composition;
Bone Density*;
Cohort Studies*;
Cross-Sectional Studies;
Female;
Humans;
Muscle, Skeletal*;
Retrospective Studies*;
Risk Factors
- From:Obstetrics & Gynecology Science
2015;58(2):135-143
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To determine the impact of the changes in the amount of abdominal fat, directly measured by computed tomography, body composition, and the metabolic syndrome (MetS) risk factors on the bone mineral density (BMD) of Korean women. METHODS: A retrospective cohort study involving 534 Korean women aged 29 to 78 years, who had undergone both dual-energy X-ray absorptiometry and abdominal adipose tissue analysis by computed tomography scan more than twice between January 2004 and December 2010. The changes in the BMD values were examined in association with the changes in fat amount, body composition parameters, and risk factors of MetS. RESULTS: On cross sectional analysis, there was a significant positive correlation between femoral BMD and total abdominal fat amount at the initial visit. However, the correlation disappeared when the impact of change of the fat amount on the change in BMD was analyzed over the study period. When the MetS and body composition parameters were analyzed, a significantly positive correlation was found between skeletal muscle mass and BMD. There was no significant relationship between the MetS risk factors or other body composition parameters and BMD throughout the study period after adjusting for age (time interval). CONCLUSION: Among body composition parameters, only increased skeletal muscle mass had a positive correlation with increased BMD over the study period of 2.7 years.
