Endometrial cancer occurence five years after breast cancer in BRCA2 mutation patient.
10.5468/ogs.2015.58.2.175
- Author:
Sang Eun OH
1
;
Soo Hyun KIM
;
Mee Seon KIM
;
Min Kyu KIM
Author Information
1. Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
BRCA;
Breast neoplasms;
Endometrial neoplasms
- MeSH:
Breast Neoplasms*;
Diagnosis;
Endometrial Neoplasms*;
Female;
Genes, BRCA2;
Genetic Counseling;
Humans;
Middle Aged;
Pathology
- From:Obstetrics & Gynecology Science
2015;58(2):175-178
- CountryRepublic of Korea
- Language:English
-
Abstract:
We recently experienced a case of endometrial cancer 5 years after the diagnosis of breast cancer in a patient with a mutation in the BRCA2 gene. A 55-year-old Korean woman who had a past history of breast cancer in her 50s underwent an operation for endometrial cancer. Final pathology confirmed stage Ia, and no adjuvant treatment was performed. After surgery, considering her history of sequential cancer occurrence, genetic counseling was offered. The result showed the BRCA2 variation of unknown significance mutation. This is the first case report of sequential cancers (endometrial and breast) in a patient with a BRCA2 mutation among a Korean population.
