A Case of Disseminated Mucormycosis after Allogenic Bone Marrow Transplantation.
- Author:
Sun Hwa KIM
1
;
Ki Bum KIM
;
Young Mi CHOO
;
Woo Im CHANG
;
Yang Soo KIM
;
Dong Gun LEE
;
Jung Hyun CHOI
;
Wan Shik SHIN
;
Chang Ki MIN
;
Chun Choo KIM
Author Information
1. Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Mucormycosis;
Immunocompromised host;
Amphotericin B;
Liposomal amphotericin B
- MeSH:
Adult;
Amphotericin B;
Ants;
Bone Marrow Transplantation*;
Bone Marrow*;
Communicable Diseases;
Cyclosporine;
Debridement;
Diabetes Mellitus;
Diagnosis;
Emergency Service, Hospital;
Fever;
Flank Pain;
Flucytosine;
Hematologic Neoplasms;
Humans;
Hyphae;
Immunocompromised Host;
Kidney;
Lung;
Mortality;
Mucormycosis*;
Prednisolone;
Spleen;
Steroids
- From:Korean Journal of Infectious Diseases
2000;32(1):73-77
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Disseminated mucormycosis is a rare fungal infectious disease with a high mortality rate and is infrequently diagnosed ante mortem. It is most frequently seen in immunocompromised hosts such as diabetes mellitus, hematologic malignancies, or in the long-term use of steroids or chemotherapeutic agents. Tissue invasion by the hyphae of mucormycosis must be seen microscopically to establish the diagnosis. Treatment consists of correction of the predisposing condition, surgical debridement, and amphotericin-B therapy. A 35-year-old man was admitted through the emergency room due to fever and the right flank pain. He had received an allogenic bone marrow transplantation eight months ago and had been medicated with prednisolone and cyclosporine since the procedure. He was diagnosed with disseminated mucormycosis that involved the spleen, right kidney, and right lung. He is being successfully treated with amphotericin B, flucytosine, and liposomal amphotericin B.
