Fatal Cytomegalovirus Pneumonia in a Immunocompetent Patient.
- Author:
Woo Im CHANG
1
;
Jung Hwan OH
;
Hae Won HAN
;
Sun Hwa KIM
;
Yang Soo KIM
;
Seong Hyun SON
;
Dong Gun LEE
;
Jung Hyun CHOI
;
Wan Shik SHIN
Author Information
1. Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Cytomegalovirus pneumonia;
Immunocompetent;
Ganciclovir
- MeSH:
Cause of Death;
Cytomegalovirus*;
Fatal Outcome;
Female;
Fever;
Foscarnet;
Ganciclovir;
Great Britain;
Humans;
Immunocompromised Host;
Liver;
Lymphocytes;
Lymphocytosis;
Middle Aged;
Pneumonia*;
United States
- From:Korean Journal of Infectious Diseases
2000;32(1):78-81
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Serious cytomegalovirus (CMV) infection occurs frequently in immunocompromised patients and is a common cause of death. Although primary infection in immunocompetent hosts is normally subclinical, mononucleosis-like syndrome that is characterized by malaise, protracted fever, mild liver function abnormalities, and lymphocytosis with atypical lymphocytes occurs in -10% of patients. Rarely fulminant infection may develop. In both the United States and the United Kingdom, ganciclovir and foscarnet are recommended for the treatment of serious CMV infections in immunocompromised patients. In contrast, there are no recommendations for treatment of severe CMV disease in immunocompetent patients. We describe a case of 45-year-old woman with CMV pneumonia with a fatal outcome for whom there was no evidence of prior immunodeficiency.
