Prenatal detection of de novo inversion of chromosome 9 with duplicated heterochromatic region and postnatal follow-up.
- Author:
Jeong Joong KIM
1
;
Hee Sub RHEE
;
Yeun Tai CHUNG
;
So Yeon PARK
;
Soo Kyung CHOI
Author Information
1. Department of Anatomy, School of Medicine, Wonkwang University, Iksan, Korea.
- Publication Type:Case Reports
- Keywords:
heterochromatic duplication;
pericentric inversion;
de novo inversion
- MeSH:
Adult;
Case Report;
Chromosome Aberrations*;
Chromosome Banding;
Chromosomes, Human, Pair 11;
Chromosomes, Human, Pair 9*;
Female;
Gene Duplication;
Human;
In Situ Hybridization, Fluorescence;
Inversion (Genetics);
Karyotyping;
Phenotype;
Pregnancy;
Prenatal Diagnosis*;
Translocation (Genetics)
- From:Experimental & Molecular Medicine
1999;31(3):134-136
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report the first de novo case of a heterochromatic duplication on the long arm of the chromosome 9, which then was pericentrically inverted at p11q13. This condition was detected prenatally and carry to term. We then performed the follow up for over 1 year. So far, there seems to be no phenotypical abnormalities.
