Primary Hyperparathyroidism with Extensive Brown Tumors and Multiple Fractures in a 20-Year-Old Woman.
10.3803/EnM.2015.30.4.614
- Author:
Ju Hee CHOI
1
;
Kyoung Jin KIM
;
Ye Jin LEE
;
Sun Hwa KIM
;
Sin Gon KIM
;
Kwang Yoon JUNG
;
Dong Seop CHOI
;
Nam Hoon KIM
Author Information
1. Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. pourlife@naver.com
- Publication Type:Case Report
- Keywords:
Brown tumor;
Hyperparathyroidism;
Parathyroid neoplasms
- MeSH:
Female;
Humans;
Hyperparathyroidism;
Hyperparathyroidism, Primary*;
Osteoclasts;
Parathyroid Neoplasms;
Young Adult*
- From:Endocrinology and Metabolism
2015;30(4):614-619
- CountryRepublic of Korea
- Language:English
-
Abstract:
A brown tumor is a benign fibrotic, erosive bony lesion caused by localized, rapid osteoclastic turnover, resulting from hyperparathyroidism. Although brown tumors are one of the most pathognomonic signs of primary hyperparathyroidism, they are rarely seen in clinical practice. In this report, we present a case of 20-year-old woman with recurrent fractures and bone pain. Plain digital radiographs of the affected bones revealed multiple erosive bone tumors, which were finally diagnosed as brown tumors associated with primary hyperparathyroidism due to a parathyroid adenoma. This case shows that multiple, and clinically severe form of brown tumors can even occur in young patients.
