A Case of Combined Hepatocellular-Cholangiocarcinoma with Underlying Schistosomiasis.
10.3904/kjim.2007.22.4.283
- Author:
Chang Kyun HONG
1
;
Jin Mo YANG
;
Bong Koo KANG
;
Jin Dong KIM
;
Young Chul KIM
;
U Im CHANG
;
Jin Young YOO
Author Information
1. Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. jmyangdr@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Carcinoma;
Hepatocellular;
Cholangiocarcinoma;
Schistosomiasis
- MeSH:
Adenocarcinoma/diagnosis/pathology/surgery;
Adult;
Carcinoma, Hepatocellular/*diagnosis/pathology/surgery;
Cholangiocarcinoma/*diagnosis/pathology/surgery;
Female;
Humans;
Schistosomiasis/*physiopathology
- From:The Korean Journal of Internal Medicine
2007;22(4):283-286
- CountryRepublic of Korea
- Language:English
-
Abstract:
Combined hepatocellular-cholangiocarcinoma is a rare form of primary liver cancer showing features of both hepatocellular and biliary epithelial differentiation. We report here on a case with collision tumor, which apparently was the coincidental occurrence of both hepatocellular carcinoma and cholangiocarcinoma underlying schistosomiasis. A 39-year-old-Philippine female was transferred to our hospital for evaluation of a liver mass that was found on ultrasonography at a local hospital. HBsAg and Anti-HCV were negative and serum alpha-fetoprotein (AFP) level was normal. The tumor mass was histologically diagnosed as adenocarcinoma by sono-guided biopsy before the operation. Partial lobectomy was performed and we histologically identified the concurrent occurrence of hepatocellular carcinoma and cholangiocarcinoma, (a "collision type carcinoma").