Efficacy of Takushato on Patients with Dizziness and Vertigo in Relation to Signs and Symptoms of Fluid Retention
10.3937/kampomed.62.615
- VernacularTitle:沢瀉湯の臨床効果と水毒徴候の関連について
- Author:
Tetsuro OIKAWA
;
Yoshitaka YONETA
;
Sea-Bong HYUN
;
Hiroshi ODAGUCHI
;
Akino WAKASUGI
;
Takeshi INO
;
Kazuhiro HASHIGUCHI
;
Yoichiro TAKIGUCHI
;
Toshihiko HANAWA
- Publication Type:Journal Article
- Keywords:
takushato, dizziness, vertigo, fluid retention, vestibular function test
- From:Kampo Medicine
2011;62(5):615-620
- CountryJapan
- Language:Japanese
-
Abstract:
Takushato is a Kampo formula used for the treatment of dizziness and vertigo. Signs and symptoms suggestive of fluid retention have been regarded as clinical indications for takushato administration, but it is not clear if improvement of these signs and symptoms is related to the clinical efficacy of takushato, so we analyzed the correlation among these factors. Twenty patients who suffered from dizziness and vertigo were treated with takushato for 4 weeks. Before and after treatment, subjective symptoms and objective data including vestibular function tests were assessed, and correlation among the factors was analyzed. Improvement of patients' total symptoms was significantly correlated with improvement of fluid retention scores. Furthermore, improvement in vestibular function tests showed a trend toward correlation with that of fluid retention scores.These results suggest that improvement in the signs and symptoms of fluid retention is related to the clinical efficacy of takushato. We conclude that the presence of fluid retention is a reasonable clinical indication for takushato administration.
