Primary Large Cell Neuroendocrine Carcinoma of the Breast: Radiologic and Pathologic Findings.
10.3346/jkms.2008.23.6.1118
- Author:
Jin Woo KIM
1
;
Ok Hee WOO
;
Kyu Ran CHO
;
Bo Kyung SEO
;
Hwan Seok YONG
;
Aeree KIM
;
Eun Young KANG
Author Information
1. Department of Radiology, College of Medicine, Korea University Guro Hospital, Seoul, Korea. wokhee@unitel.co.kr
- Publication Type:Case Report ; Research Support, Non-U.S. Gov't
- Keywords:
Breast;
Ultrasonography;
Tomography, X-Ray Computed;
Large Cell Neuroendocrine Carcinoma
- MeSH:
Adult;
Breast Neoplasms/*diagnosis/pathology/ultrasonography;
Carcinoma, Large Cell/*diagnosis/pathology/radiography;
Carcinoma, Neuroendocrine/*diagnosis/pathology/radiography;
Diagnosis, Differential;
Female;
Humans;
Tomography, X-Ray Computed
- From:Journal of Korean Medical Science
2008;23(6):1118-1120
- CountryRepublic of Korea
- Language:English
-
Abstract:
Some breast neoplasms are classified as primary neuroendocrine carcinomas because they are positive for neuroendocrine markers. Although neuroendocrine carcinomas can originate from various organs of the body, primary neuroendocrine carcinomas of the breast are extremely rare. The diagnosis of primary neuroendocrine carcinoma of the breast can only be made if nonmammary sites are confidently excluded or if an in situ component can be found. Here we report a primary large-cell neuroendocrine carcinoma (LCNL) involving the left breast. Breast ultrasonography revealed a lobulated, heterogeneous, low-echoic mass in the left breast, and the lesion ap-peared as a well-defined, highly-enhancing mass on a chest computed tomography scan. Ultrasound-guided core needle biopsy was performed on the mass, and primary LCNC was confirmed by histopathologic examination.