A Case of Abdominal Aortic Aneurysm in Association with Congenital Factor XI Deficiency
10.4326/jjcvs.40.279
- VernacularTitle:先天性第 XI 因子欠乏症を伴った腹部大動脈瘤症例に対する1治験例
- Author:
Yoshiyuki Nishimura
;
Toshiharu Ishii
;
Yasuhide Ookawa
- Publication Type:Journal Article
- Keywords:
congenital factor XI deficiency;
abdominal aortic aneurysm;
activated partial thromboplastin time (APTT)
- From:Japanese Journal of Cardiovascular Surgery
2011;40(6):279-281
- CountryJapan
- Language:Japanese
-
Abstract:
Congenital factor XI deficiency is a rare intrinsic coagulation factor. We treated a 67-year-old man with abdominal aortic aneurysm, in whom activated partial thromboplastin time (APTT) found to be prolonged preoperatively. After fresh frozen plasma (FFP) was given before surgery, aneurysm was successfully replaced by a woven Dacron graft. No bleeding tendency was noted during the operation and FFP was also administered during and after surgery. The patient recovered without incident and left the hospital 13 days after the operation. Since several days are required to determine factor XI activity, APTT is useful as a parameter of coagulation factor activity in the perioperative period.
