A Case of Immunoglobulin G4-Related Cardiac Tumor around the Coronary Artery
10.4326/jjcvs.39.230
- VernacularTitle:IgG4 関連疾患による冠動脈周囲腫瘍の1例
- Author:
Masahiko Okamoto
;
Masashi Nagumo
;
Tetsuya Goto
;
Akihiro Yoshitake
;
Takahisa Miki
;
Koji Osumi
- Publication Type:Journal Article
- Keywords:
IgG4-related disease, cardiac tumor, periarterial mass lesion, coronary artery
- From:Japanese Journal of Cardiovascular Surgery
2010;39(4):230-233
- CountryJapan
- Language:Japanese
-
Abstract:
Immunoglobulin G4 (IgG4)-related disease can occur in various organs, most of which comprise glandular or ductal tissue. We report a case of IgG4-related disease which occurred in a cardiovascular lesion. A 69-year-old man was found to have a tumorous lesion around the coronary artery. Open chest biopsy showed the diffuse lymphoplasmacytic infiltration, occasional eosinophils and numerous IgG4-positive plasma cells within the lesions. The serum concentration of IgG4 in the postoperative period was 1,080 mg/dl (reference range, <135). We diagnosed IgG4-related periarteritis manifesting as a tumor around the coronary artery. This case suggests that IgG4-related disease can occur around the coronary artery and manifest as a periarterial mass lesion.