Clinical Evaluation of Oxidative Stress after Taking Powdered Processed Aconiti Tuber
- Author:
Hajime NAKAE
- Publication Type:Journal Article
- Keywords:
oxidative stress;
total antioxidant capacity;
processed Aconiti tuber
- From:Kampo Medicine
2010;61(1):15-18
- CountryJapan
- Language:Japanese
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Abstract:
‘Processed bushi powder for ethical dispensing’, or TJ-3022, is an Aconiti tuber (PAT) herbal drug, and TJ-3023 is newly-developed to contain a higher proportion of diester aconitine alkaloid. We measured reactive oxygen metabolite derivative levels (d-ROMs tests), and total antioxidant capacity (OXY-adsorbent tests) in healthy adult volunteers, to assess whether PAT affects the oxidative stress regulation system. Thirty-four subjects were assigned to one of two groups: a TJ-3022 group and a TJ-3023 group. No significant chronological differences were observed in the TJ-3022 group. No significant chronological differences were observed in the TJ-3023 group, either. These results indicate that PAT dose not affect the oxidative stress regulation system in humans.
