The Unique Correlation between Anti-Mutagenicity of Human Saliva and Change in Body Weight
10.1265/ehpm.6.82
- Author:
Masahiro TODA
;
Kanehisa MORIMOTO
;
Sei-ichi NAKAMURA
;
Takashi UMEDA
;
Shigeyuki NAKAJI
;
Kazuo SUGAWARA
- Publication Type:Journal Article
- Keywords:
anti-mutagenicity;
human saliva;
umu test;
fasting;
judo players
- MeSH:
Saliva;
competition;
Human;
Body Weight;
g <3>
- From:Environmental Health and Preventive Medicine
2001;6(2):82-87
- CountryJapan
- Language:Japanese
-
Abstract:
The purpose of this study was to investigate the effect of weight reduction on the anti-mutagenicity of human saliva. Subjects were 16 male college judo players. The anti-mutagenicity of the saliva was measured using the umu test. There was an inhibiting effect of the saliva on the mutagenicity of AF-2. However, a modifying effect of the saliva on Trp-P-1 was not observed. On the day before a competition and 7 days after the competition, the inhibiting capacity of the saliva for the mutagenicity of AF-2 decreased and increased in two non-weight reduction and two weight reduction groups, respectively. However, on the day before the competition, the changed body weights (r=−0.77, p<0.01) and BMI (r=−0.77, p<0.01) were significantly correlated with that of the inhibiting capacity of the saliva for the mutagenicity of AF-2. In addition, the BMI at 20 days before the competition was not significantly but markedly correlated with it (r=0.50, p=0.057). At 7 days after the competition, however, these correlations were not found. These findings suggest a unique correlation between the anti-mutagenicity of human saliva and body weight or BMI.
