A Case of Seizure and Metabolic Acidosis Due to Renal Adjustment Dosage of Isoniazid in an Elderly Woman.
- Author:
Young Shin SHIN
1
;
Eun Hee SIM
;
Chang Woo YEO
;
Jin Doo KANG
;
Ji Yeon KIM
;
Seon Ja PARK
Author Information
- Publication Type:Case Report
- Keywords: Isoniazid; Metabolic acidosis; Pyridoxine; Seizure
- MeSH: Acid-Base Equilibrium; Acidosis*; Aged*; Coma; Female; Humans; Isoniazid*; Parents; Pyridoxine; Seizures*
- From:Kosin Medical Journal 2014;29(1):63-68
- CountryRepublic of Korea
- Language:Korean
- Abstract: Isoniazid is one of the most commonly used antituberculosis drug. Acute into xication is characterized by repetitious convulsions, high anion gap metabolic a cidosis and coma. The basis of theraphy consists of parental pyridoxine admi nistration in a dose equivalent to that of isoniazid ingested. Here we present a case of seizure and metabolic acidosis due to only renal adjustment dosage of Isoniazid in an elderly woman.
