Influence of electromagnetic fields on bone fracture in rats: role of CAPE.
- Author:
Ekrem CICEK
1
;
Osman GOKALP
;
Remzi VAROL
;
Gokhan CESUR
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Biomechanical Phenomena; Bone Density; Caffeic Acids; administration & dosage; Electromagnetic Fields; Femur; pathology; Fractures, Bone; prevention & control; Male; Phenylethyl Alcohol; administration & dosage; analogs & derivatives; Radiation Injuries, Experimental; prevention & control; Radiation-Protective Agents; administration & dosage; Rats; Rats, Sprague-Dawley
- From: Biomedical and Environmental Sciences 2009;22(2):157-160
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo study the effects of radiation emitted by mobile phones on bone strength and caffeic acid phenethyl ester (CAPE) on the changes induced by radiation.
METHODSForty-eight Sprague-Dawley rats were divided into five groups. Rats in the control group (first group) were left within the experimental setup for 30 min/day for 28 days without radiation exposure. Nine hundred MHz radiation group was broke down into 2 subgroups (group 1/2). Both subgroups were exposed to radiation for 28 days (30 min/day). The next group was also divided into 2 subgroups (group 3/4). Each was exposed to 1800 MHz of radiation for 28 days (30 min/day). The third and fifth groups were also treated with CAPE for 28 days. Treatment groups received ip caffeic acid phenethyl ester (10 micromol/kg per day) before radiation session. Bone fracture was analyzed.
RESULTSBreaking force, bending strength, and total fracture energy decreased in the irradiated groups but increased in the treatment groups.
CONCLUSIONRadiation and CAPE can significantly improve bone.
