The correlation between plasma calprotectin and neutrophil count in patients with aggressive periodontitis.
- Author:
Xiaojun SUN
1
;
Huanxin MENG
2
;
Dong SHI
1
;
Zhibin CHEN
1
Author Information
- Publication Type:Journal Article
- MeSH: Aggressive Periodontitis; blood; immunology; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Humans; Leukocyte Count; Leukocyte L1 Antigen Complex; blood; Neutrophils; Plasma
- From: Chinese Journal of Stomatology 2014;49(11):649-651
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo measure the levels of plasma calprotectin in aggressive periodontitis (AgP) patients and to analyze the relationship between the plasma calprotectin and neutrophil count.
METHODSVenous blood samples were collected from 61 AgP patients and 48 periodontally healthy controls. Clinical examination consisted of bleeding index (BI), probing depth (PD), attachment loss measurements (AL) and percentage of severe sites. Plasma level of calprotectin was determined by enzyme-linked immunosorbent assay.
RESULTSThe plasma concentrations of calprotectin in AgP patients [(2.1±1.1) mg/L] were significantly higher than those in healthy controls[(1.5±0.6) mg/L] (P < 0.01). The plasma concentration of calprotectin in AgP patients was positively correlated with BI (r = 0. 271, P = 0.035), PD (r = 0.437, P = 0.000), AL (r = 0.450, P = 0.000) and percentage of severe sites (r = 0.423, P = 0.001). While the neutrophil count was also positively correlated with the plasma concentrations of calprotectin in AgP patients (r = 0.380, P = 0.004).
CONCLUSIONSAgP may have impact on the elevation of plasma level of calprotectin.
